Immediately a very strong opening with Maddy's Theme, those textures and melodically dissonant synths work PERFECT for setting the mood of a creepy experimental facility. Only real notes would be to consider cycling through some more synths to keep it fresh.
Fabulous atmosphere for The Facility and The Chamber, no notes. Stereo field is clean, textures are great, and that low bass is perfectly placed.
Malformation is a great step-up in thematic intensity, the drums add a lot especially with how ambient the rest of the OST is.
Overall really great ambient set that totally fits the vibe you described. Loved all the sound design choices.