This is quite interesting, but the learning curve is pretty steep. I'd have two suggestions:
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Give the player control over when the numbers are placed on the line, so there's more time to plan.
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Start slower. Maybe at first only with + and -1, then introduce a new number like 2 or 3, then introduce multiplication, and after that, powers of two. After that, you can start with two numbers at once. Right now, it’s a bit overwhelming and fast... at least for me.
I like it because of its creativity. I think it has good potential :)