Cool concept and yeah lobotomy is definetely not a safe practice!
But I have to say that I didn't really feel the risky theme because the lobotomy here is somthing that you basically have to do to get stronger (It's not a risk and reward mechanic which requires agency)
It took me a while to understand how to shoot and I suggest a couple of things about this:
- you can write the controls on the first room floor (like in Isacc)
- make the "confirm" for the lobotomy something like "press any key" instead of using the mouse because if players starts use it they will be more inclined to consider using it for shooting as well
Hope this feedback will be helpfull!
P.S. The volumes definitely need to be adjusted...