I trying to make a system based on the five elements of Chinese culture and they oppose each other, I want cards that make certain other cards weaker or destroy others when played. Is this possible?

Deckbuilder Combat System for your games · By
Are you trying to play those two opposing cards simultaneously? If so, no that is not currently supported by the plugin. You can theoretically have the player play their card and then show the enemy's card without playing it using the Show Card plugin command and then resolve them manually through Eval Card Actions.