I wish more debuffs gave you special unique abilities when they were on you. Currently it's only the lava making you jump higher and that mechanic is really interesting. I feel like if you got something from the debuffs and they lasted a lot shorter, it would make planning a level a lot more interesting as your health becomes a resource you need to use for platforming (Not like Paralyze though I think that ones a bit annoying)
Besides that though the idea is really funny I love becoming the world's most afflicted man and running around in a dungeon