If you have a MacBook and want to run the game without CrossOver: I downloaded the Linux version, extracted the game files from it, and opened them with the official Godot 4.4.1 for macOS. I ended up with a normal native .app application for Mac. I only did this for my own purchased copy of the game. (Ask an AI how to do it.)
If your microphone sounds choppy, glitchy, or delayed, changing the sample rate to 44.1 kHz helped me. On Mac: open Audio MIDI Setup (Applications → Utilities), select both your microphone/input device and your speakers or headphones/output device, and set their Format to the same sample rate — in my case, 44,100 Hz. Then fully restart the game.