The potions either poison/slow you or give your hastened movement speed which is useful for completing the maze quickly and outrunning the red orbs at end. You are penalized whenever you must "trust" the orb and interact with them. You dont have to cleanse them but if you need to or want to you can but once again "lose trust". The trust bar is works kinda both as a health bar but also as a measurement of the player gradually losing any trust in the orbs at all. And yes it is random. Each map is procedurally generated! However there are pretty easier to identify patterns which make navigating very easy once you figure them out. I think one tip I give people is to think of the orbs like mini checkpoints. A start commonly used is to "trust no one" and just use the orbs colors to track where you have been before. Thanks for the feedback