First impression of screen: I'm just some dude who doesn't know this genre, but it felt like a lot of information at once. I imagine you are quite used to it, and so may not see how it feels to a first-time player. I'd encourage a simpler screenshot that's almost like App Store ones explaining the mechanics and what makes your game different, with that screenshotted UI being built towards over time.
I actually dig the page, it feels like Geocities. But the game itself - very information dense and now it's animating. I'd clip down to the essentials and maybe add some Word Art. I'm being fully serious by the way.
OK game itself is doing what I just typed above - so well done. Music slaps. Mysterious and important. The twitch overlay is fighting with your "x" button which may leave a lot of players confused. Not a problem with my platform by the way ;)
The music reminds me of "My Little Box" from Ghost Ship, coupled with some Resident Evil (https://en.wikipedia.org/wiki/Resident_Evil_(2002_film)) style music. Maybe a little bleak at first but it builds beautifully.
The only reason I'm not playing it more is because I have to keep working. But, overall well done.
If you'd ever like to watch how other first-time players get through those first minutes, I make Betacade (betacade.com) and I'd be happy to set you up.