First time I play a game that uses a brain as a stage, it is an interesting choice.
I lost by clicking the brain too much in my first playthrough, I think the outcome wasn't clear.
I think the icons should have a collider slightly larger than sprite size, otherwise it feels a little unfair.
Clicking icons feedback is a little too much imo, it covers a lot of screen.
Sometimes the icon explosion feebacks spawns in the wrong position.
Losing health after "bad" dialogue choices feels unfair.
It starts too slow once you already know the basics.
Background felt too static.
I stopped playing after 4 attempts.
I hope the feedback helps.