WOW really great piece! I really love all of the character designs here, they all feel really unique and well designed, and you used the color pallet well!
But where this piece really shines for me, is the animation. It is superb, you really made the scene feel alive with it! And I can tell it is really high quality! All of the animation really expresses the characters in a meaningful way and that is an incredible difficult thing to do! (I also really like the utilization of sub-pixel animation in some places, you did great with it!)
The being said my only critique would be the AA (Anti Aliasing), where I feel like you could have utilized a little more around the piece! (and also a really tiny mistake that I saw, is that there seems to be a line right under the characters neck (in the character portrait on the bottom left).
Regardless, these are just tiny nitpicks that I had, and I don't really feel that they take anything out of the piece!
Good job!