While I definitely recognize the massive undertaking a game of this scale is to execute on, I would echo the sentiment that a lot of people felt and that was the real time waiting made me bounce off of this super hard. I basically opened it up, clicked upgrade on all the things I could and then just sat there wondering what I should do next, after a little bit of poking around I kinda felt like maybe there wasn't anything I could do but wait.
I think this type of game would work well as one of those desktop games that sits right above the task bar or whatever, like desktop fishing etc.
Good job on the general polish and feel but for me it didn't feel like there was much game, it reminded me a lot of old Facebook games where you spend energy and then wait (or pay) for your missions to complete.