Still, if you are really interested in bedding a character who isn't attracted by you, I've tested that adding inclinations (which you can freely) like "sl√t", "f√ckbuddy" and else, it's much more likely that they will accept (with high lust and/or romance).
In earlier versions of the game, you could convince NPCs to sleep with PC even if you weren't their orientation. This was a bug that has since been fixed. If you're still able to fuck NPCs who you don't match the orientation of, that's still a bug